Improving Skin Lesion Segmentation with Self-Training.

Skin lesion segmentation plays a key role in the diagnosis of skin cancer; it can be a component in both traditional algorithms and end-to-end approaches. The quality of segmentation directly impacts the accuracy of classification; however, attaining optimal segmentation necessitates a substantial amount of labeled data. Semi-supervised learning allows for employing unlabeled data to enhance the results of the machine learning model. In the case of medical image segmentation, acquiring detailed annotation is time-consuming and costly and requires skilled individuals so the utilization of unlabeled data allows for a significant mitigation of manual segmentation efforts. This study proposes a novel approach to semi-supervised skin lesion segmentation using self-training with a Noisy Student. This approach allows for utilizing large amounts of available unlabeled images. It consists of four steps-first, training the teacher model on labeled data only, then generating pseudo-labels with the teacher model, training the student model on both labeled and pseudo-labeled data, and lastly, training the student* model on pseudo-labels generated with the student model. In this work, we implemented DeepLabV3 architecture as both teacher and student models. As a final result, we achieved a mIoU of 88.0% on the ISIC 2018 dataset and a mIoU of 87.54% on the PH2 dataset. The evaluation of the proposed approach shows that Noisy Student training improves the segmentation performance of neural networks in a skin lesion segmentation task while using only small amounts of labeled data.

Orthogonal mode couplers for plasmonic chip based on metal-insulator-metal waveguide for temperature sensing application.

In this work, a plasmonic sensor based on metal-insulator-metal (MIM) waveguide for temperature sensing application is numerically investigated via finite element method (FEM). The resonant cavity filled with PDMS polymer is side-coupled to the MIM bus waveguide. The sensitivity of the proposed device is ~ - 0.44 nm/°C which can be further enhanced to - 0.63 nm/°C by embedding a period array of metallic nanoblocks in the center of the cavity. We comprehend the existence of numerous highly attractive and sensitive plasmonic sensor designs, yet a notable gap exists in the exploration of light coupling mechanisms to these nanoscale waveguides. Consequently, we introduced an attractive approach: orthogonal mode couplers designed for plasmonic chips, which leverage MIM waveguide-based sensors. The optimized transmission of the hybrid system including silicon couplers and MIM waveguide is in the range of - 1.73 dB to - 2.93 dB for a broad wavelength range of 1450-1650 nm. The skillful integration of these couplers not only distinguishes our plasmonic sensor but also positions it as a highly promising solution for an extensive array of sensing applications.

Design and development of a miniature mid-infrared linear variable filter based spectrometer for environmental sensing.

Miniaturized, energy-efficient and application-specific spectral sensing systems promise to be a highly sought-after technology in the coming years, with potential applications in areas such as: distributed sensor systems, IoT devices, mobile autonomous platforms, and many others. We present in this work the design, construction and measurement results of a compact, mid-infrared spectrometer working in the 3 - 4 µm spectral region, attractive for applications requiring the identification of polymer materials. The spectrometer is based on linear-variable filters (LVF) combined with an uncooled HgCdTe linear-detector array (LDA). The design and architecture of the device is described and discussed in the context of miniaturization challenges and constraints. Measured spectra of thin polyimide and polystyrene foils are presented to prove the applicability of the developed device to polymer materials detection and identification.

Breakthrough in Silicon Photonics Technology in Telecommunications, Biosensing, and Gas Sensing.

Silicon photonics has been an area of active research and development. Researchers have been working on enhancing the integration density and intricacy of silicon photonic circuits. This involves the development of advanced fabrication techniques and novel designs to enable more functionalities on a single chip, leading to higher performance and more efficient systems. In this review, we aim to provide a brief overview of the recent advancements in silicon photonic devices employed for telecommunication and sensing (biosensing and gas sensing) applications.

A Top-Down Approach and Thermal Characterization of Luminescent Hybrid BPA.DA-MMA@Ln2L3 Materials Based on Lanthanide(III) 1H-Pyrazole-3,5-Dicarboxylates.

In this study, novel hybrid materials exhibiting luminescent properties were prepared and characterized. A top-down approach obtained a series of polymeric materials with incorporated different amounts (0.1; 0.2; 0.5; 1, and 2 wt.%) of dopants, i.e., europium(III) and terbium(III) 1H-pyrazole-3,5-dicarboxylates, as luminescent sources. Methyl methacrylate and bisphenol A diacrylate monomers were applied for matrix formation. The resulting materials were characterized using Fourier transform infrared spectroscopy (FTIR) and thermal analysis methods (TG-DTG-DSC, TG-FTIR) in air and nitrogen atmosphere, as well as by luminescence spectroscopy. The homogeneity of the resulting materials was investigated by means of optical microscopy. All obtained materials exhibited good thermal stability in both oxidizing and inert atmospheres. The addition of lanthanide(III) complexes slightly changed the thermal decomposition pathways. The main volatile products of materials pyrolysis are carbon oxides, water, methyl methacrylic acid and its derivatives, bisphenol A, 4-propylphenol, and methane. The luminescence properties of the lanthanide complexes and the prepared hybrid materials were investigated in detail.

Optical Thin Films Fabrication Techniques-Towards a Low-Cost Solution for the Integrated Photonic Platform: A Review of the Current Status.

In the past few decades, several methods concerning optical thin films have been established to facilitate the development of integrated optics. This paper provides a brief depiction of different techniques for implementing optical waveguide thin films that involve chemical, physical, and refractive index modification methods. Recent advances in these fabrication methods are also been presented. Most of the methods developed for the realization of the thin-films are quite efficient, but they are expensive and require sophisticated equipment. The major interest of the scientists is to develop simple and cost-effective methods for mass production of optical thin films resulting in the effective commercialization of the waveguide technology. Our research group is focused on developing a silica-titania optical waveguide platform via the sol-gel dip-coating method and implementing active and passive optical elements via the wet etching method. We are also exploring the possibility of using nanoimprint lithography (NIL) for patterning these films so that the fabrication process is efficient and economical. The recent developments of this platform are discussed. We believe that silica-titania waveguide technology developed via the sol-gel dip-coating method is highly attractive and economical, such that it can be commercialized for applications such as sensing and optical interconnects.

Subwavelength Grating Waveguide Structures Proposed on the Low-Cost Silica-Titania Platform for Optical Filtering and Refractive Index Sensing Applications.

The sol−gel dip-coating method is a cost-efficient way for the realization of thin films on a planar substrate. In this work, high-quality, low-loss, and low-surface roughness silica−titania thin films are deposited on a glass substrate with the sol−gel dip-coating method. This platform works in the visible to near-IR wavelength ranges and can be useful for several eye-catching photonic components. The paper is comprised of two parts: the first part deals with the development of a low-cost silica−titania waveguide system, whereas the second part provides detail on the numerical modeling of the SWG waveguide filter and SWG waveguide FP-sensor design. The SWG waveguide NIR-stopband filter can achieve an ER of >40 dB and 3-dB bandwidth of 110 nm designed at optimized parameters. The SWG waveguide-FP structure proposed in this work act as a refractive index sensor where the sensitivity is ~120 nm/RIU by reducing the width of the waveguide. This sensitivity can be further enhanced by reducing the waveguide height. We believe that this work is quite important for the realization of low-cost integrated photonic devices based on the silica−titania platform developed via the sol−gel dip-coating method.

Passive Photonic Integrated Circuits Elements Fabricated on a Silicon Nitride Platform.

The fabrication processes for silicon nitride photonic integrated circuits evolved from microelectronics components technology-basic processes have common roots and can be executed using the same type of equipment. In comparison to that of electronics components, passive photonic structures require fewer manufacturing steps and fabricated elements have larger critical dimensions. In this work, we present and discuss our first results on design and development of fundamental building blocks for silicon nitride integrated photonic platform. The scope of the work covers the full design and manufacturing chain, from numerical simulations of optical elements, design, and fabrication of the test structures to optical characterization and analysis the results. In particular, technological processes were developed and evaluated for fabrication of the waveguides (WGs), multimode interferometers (MMIs), and arrayed waveguide gratings (AWGs), which confirmed the potential of the technology and correctness of the proposed approach.

Mode Sensitivity Exploration of Silica-Titania Waveguide for Refractive Index Sensing Applications.

In this paper, a novel and cost-effective photonic platform based on silica-titania material is discussed. The silica-titania thin films were grown utilizing the sol-gel dip-coating method and characterized with the help of the prism-insertion technique. Afterwards, the mode sensitivity analysis of the silica-titania ridge waveguide is investigated via the finite element method. Silica-titania waveguide systems are highly attractive due to their ease of development, low fabrication cost, low propagation losses and operation in both visible and near-infrared wavelength ranges. Finally, a ring resonator (RR) sensor device was modelled for refractive index sensing applications, offering a sensitivity of 230 nm/RIU, a figure of merit (FOM) of 418.2 RIU-1, and Q-factor of 2247.5 at the improved geometric parameters. We believe that the abovementioned integrated photonics platform is highly suitable for high-performance and economically reasonable optical sensing devices.

A Numerical Investigation of a Plasmonic Sensor Based on a Metal-Insulator-Metal Waveguide for Simultaneous Detection of Biological Analytes and Ambient Temperature.

A multipurpose plasmonic sensor design based on a metal-insulator-metal (MIM) waveguide is numerically investigated in this paper. The proposed design can be instantaneously employed for biosensing and temperature sensing applications. The sensor consists of two simple resonant cavities having a square and circular shape, with the side coupled to an MIM bus waveguide. For biosensing operation, the analytes can be injected into the square cavity while a thermo-optic polymer is deposited in the circular cavity, which provides a shift in resonance wavelength according to the variation in ambient temperature. Both sensing processes work independently. Each cavity provides a resonance dip at a distinct position in the transmission spectrum of the sensor, which does not obscure the analysis process. Such a simple configuration embedded in the single-chip can potentially provide a sensitivity of 700 nm/RIU and -0.35 nm/°C for biosensing and temperature sensing, respectively. Furthermore, the figure of merit (FOM) for the biosensing module and temperature sensing module is around 21.9 and 0.008, respectively. FOM is the ratio between the sensitivity of the device and width of the resonance dip. We suppose that the suggested sensor design can be valuable in twofold ways: (i) in the scenarios where the testing of the biological analytes should be conducted in a controlled temperature environment and (ii) for reducing the influence on ambient temperature fluctuations on refractometric measurements in real-time mode.

Thermal, Spectroscopy and Luminescent Characterization of Hybrid PMMA/Lanthanide Complex Materials.

Novel hybrid materials based on the poly(methyl methacrylate) (PMMA) matrix and lanthanide(III) carboxylates Eu:2,6-DClB and Tb:2,6-DClB were synthesized and carefully analyzed in the context of their potential application in optically active polymer-based optical fibers. To determine the usefulness of the obtained materials, a careful thermal, mass spectroscopy, and optical characterization was performed, focusing on the features critical for the technology of optical fiber processing. In addition, the luminescent features of both lanthanide complexes and the resulting hybrid composites were carefully investigated to identify the processes responsible for light emission and to analyze the influence of the PMMA host on light emission intensity and spectral characteristics. The obtained results showed that both lanthanide carboxylate complexes exhibited intense luminescence in the red and green spectral range, typical of europium and terbium dopants, and that those features were well preserved after introducing them into the PMMA polymer. Thermal analysis also proved that introducing the luminescent additives did not significantly affect the thermal properties of both hybrid materials, thus enabling further processing into the form of optical fibers.

Photonic Integrated Interrogator for Monitoring the Patient Condition during MRI Diagnosis.

In this work, we discuss the idea and practical implementation of an integrated photonic circuit-based interrogator of fiber Bragg grating (FBG) sensors dedicated to monitoring the condition of the patients exposed to Magnetic Resonance Imaging (MRI) diagnosis. The presented solution is based on an Arrayed Waveguide Grating (AWG) demultiplexer fabricated in generic indium phosphide technology. We demonstrate the consecutive steps of development of the device from design to demonstrator version of the system with confirmed functionality of monitoring the respiratory rate of the patient. The results, compared to those obtained using commercially available bulk interrogator, confirmed both the general concept and proper operation of the device.

Three-focal-spot terahertz diffractive optical element-iterative design and neural network approach.

The redistribution of an incoming radiation into several beams is necessary in telecommunication to demultiplex data signals. In the terahertz spectral range, it can be realized by easy-to-manufacture diffractive optical elements (DOEs) allowing to focus the radiation into multiple focal spots in a single plane. In this article, we present diffractive optical elements focusing THz radiation into three focal spots. Different focal spot distributions (symmetric and asymmetric) are designed using an iterative algorithm. The phase distribution forming asymmetric focal spots can be realized by iterative design, which is a novel approach, to our knowledge. Then, the structures are manufactured using a sintering-based 3D-printing method from polyamide 12 (PA 12) and measured in an experimental setup for 150 GHz frequency. A novel approach based on neural networks (NNs) is proposed to optimize the phase delay maps of the structures to further improve their performance - the higher efficiency and the lower unwanted background noise.

Deep learning-based method for the continuous detection of heart rate in signals from a multi-fiber Bragg grating sensor compatible with magnetic resonance imaging.

A method for the continuous detection of heart rate (HR) in signals acquired from patients using a sensor mat comprising a nine-element array of fiber Bragg gratings during routine magnetic resonance imaging (MRI) procedures is proposed. The method is based on a deep learning neural network model, which learned from signals acquired from 153 MRI patients. In addition, signals from 343 MRI patients were used for result verification. The proposed method provides automatic continuous extraction of HR with the root mean square error of 2.67 bpm, and the limits of agreement were -4.98-5.45 bpm relative to the reference HR.

Analysis of phase sensitivity to longitudinal strain in microstructured optical fibers.

We investigate the influence of air holes on phase sensitivity in microstructured optical fibers to longitudinal strain. According to the numerical simulations performed, large air holes in close proximity to a fiber core introduce significant compression stress to the core, which results in an increase in the effective refractive index sensitivity to longitudinal strain. The theoretical investigation is verified by an experiment performed on four fibers drawn from the same preform and differentiated by air hole diameter. We show that introducing properly designed air holes can lead to a considerable increase in normalized effective refractive index sensitivity to axial strain from -0.21 ε-1 (for traditional single mode fiber) to -0.14 ε-1.

Microstructural and optical characterization of TiO2 doped with ytterbium synthesized by sol-gel and Solar physical vapor deposition process.

Pure and ytterbium doped TiO2 nanopowders in anatase phase have been prepared by sol-gel method (SGM) and Solar Physical Vapour Deposition process (SPVD). The physico-chemical parameters of the nanopowders have been described based on the results of micro-structural characterization performed by X-ray diffractometry, scanning electron microscopy, atomic force microscopy, and nitrogen sorption measurements. Thus, final micro-structural properties of SGM and SPVD titania nanopowders have been compared in detail revealing significant changes in the structure and morphology of these two types of materials. Addition of ytterbium had no significant effect on above-mentioned properties, although it modifies significantly the optical properties of the investigated materials. The luminescent properties of developed material were found to be comparable to bulk oxide materials and better than these reported earlier for ytterbium doped titania. In particular it has been shown that the luminescence of SPVD nanopowders is significantly stronger than this of SGM samples.